De Simone Formulation
De Simone Formulation™
(Available as Visbiome in USA) and Vivomixx in Europe)
A proprietary, high-potency probiotic Product having 8 strains of live bacteria, clinically proven for gut health across all life stages – from neonates to adults – and for the management of intestinal and immune mediated disorders.
Importance of Gut Microbiota
- Gut hosts trillions of beneficial bacteria supporting digestion, immunity, and pathogen defence
- Healthy microbiota helps metabolize nutrients, detoxify harmful compounds, and strengthen immune development
- Dysbiosis is linked to IBD, IBS, obesity, allergies, autoimmune disorders, and neurological conditions
Neonate, Infant & Adult Gut Microbiota
- Gut colonization begins at birth and evolves through lactation, weaning, and adulthood
- Early microbiota dominated by Bifidobacterium, later transitioning to Firmicutes and Bacteroidetes
- Influenced by delivery mode, breastfeeding vs formula feeding, antibiotics, and diet
- Early-life microbiota development represents a critical window for long-term immunity and disease prevention
Key Features
- Available globally under brands such as Visbiome® (USA, India) and CDS-22 ™️(Europe), De Simone™️ (Korea)
- 8 strains of live bacteria, up to 900 billion CFU per serving/pack
- Backed by 100+ peer-reviewed clinical studies and over 20 years of research
- Manufactured under proprietary strain ratios developed by Professor Claudio De Simone
8
Strains of Live Bacteria
900
billion CFU per serving/pack
100+
Peer-Reviewed Clinical Studies
20+
Years of Research
Benefits
- Restores gut microbiome balance and strengthens intestinal barrier
- Proven for management of IBS, Ulcerative Colitis, Pouchitis, and Hepatic Encephalopathy
- Helps reduce intestinal permeability (“leaky gut”) linked to metabolic, immune, and neurological disorders
- Supports healthy gut colonization and immune development in neonates and infants
Clinical Attributes
- Strains include Lactobacillus, Bifidobacterium, and Streptococcus thermophilus
- Cultured from proprietary Master Cell Banks and manufactured under stringent quality standards
- Proven synergistic action between strains for maximum therapeutic efficacy
Dosing Formats
- Capsules: 10 Billion (Bn), 45 Bn and 112.5 Bn
- Powder Sachets: 225 or 450n CFU/sachet
- Extra-Strength Sachets: 900Bn CFU (prescription only)
- Drops: Easy-to-use format for neonates and infants (50B CFU per bottle)
